Background on Preeclampsia
Preeclampsia (PE) is the second-most common cause of maternal mortality worldwide and is linked to severe maternal complications like eclampsia, strokes, and organ failure. PE is defined as new-onset hypertension and proteinuria after the second trimester of pregnancy and is associated with an increased risk of chronic kidney disease and end-stage kidney disease. Initially, symptoms such as proteinuria, edema, and new-onset hypertension all impact the kidney. Preeclampsia and eclampsia are significant causes of maternal and neonatal morbidity and mortality worldwide, especially in developing countries, where it is often slower to be detected.
Once preeclampsia is identified, maternal or fetal health reduction is unavoidable. However, the early stages may be challenging to diagnose, its course unpredictable, and its deterioration can be quick. The delivery of the fetus is the only effective treatment for preeclampsia and to preserve a mother’s life. While in cases of early-onset preeclampsia, the delivery of a premature baby with all of the significant associated complications, especially in areas that do not have the most advanced preterm health care, can end in the death of the baby.