Sickle cell disease (SCD) is an inherited blood disorder that affects red blood cells causing a debilitating systemic syndrome characterized by chronic anemia. SCD causes acute painful episodes and often severely impacts the patient’s health starting at a very young age, and in severe cases, reduces life span by 20-30 years. Sickle Cell Disease can cause multi-organ failures, and kidneys are one of the most affected organs. It also affects neurological functions as children with Sickle Cell Disease (SCD) face more developmental delays and cognitive challenges than unaffected peers.
About 80% of all Sickle Cell Disease cases are known to occur in Sub-Saharan Africa, with an estimated 240,000 children4 born with SCD annually in this region. It is also becoming more common in the United States, Cuba, Central America, Saudi Arabia, India, Turkey, Greece, and it has recently been found in the UK, France, and Italy. Most experts think a medical cure is at least a few decades away; therefore, earlier symptomatic treatment is key to reducing suffering and prolonging life. Available remedies are often scarce, and diagnostic blood tests using syringes are difficult to administer and dispose of properly.